Learn about the powerful antioxidant properties of L-Carnosine and its use in various pathologies associated with oxidative stress.
Abstract Summary:
- L-Carnosine, the natural dipeptide β-alanyl-L-histidine, has antioxidant properties.
- Effective in various pathologies, especially those associated with oxidative stress.
- The article emphasizes its use in neurological and mental diseases, alcoholism, and conditions with increased free-radical processes and oxidative stress.
Other Noted Benefits:
- L-Carnosine is synthesized and found in human muscle and nervous tissues.
- It's easily absorbed in the digestive tract, crosses the blood-brain barrier, and has high bioavailability.
- L-Carnosine has a membrane-stabilizing action.
- It can impact the body's antiradical protection system.
- L-Carnosine accelerates the metabolism of cortisol and noradrenaline released into the blood under stress, reducing oxidative stress.
- It's a buffer for mixed-valence metal ions and reactive oxygen species.
- L-Carnosine can form complexes with various metal ions, which play a role in metabolic processes and can activate free-radical processes.
- It has anti-glycating and anti cross linking properties.
- L-Carnosine can form adducts with reactive and cytotoxic carbonyl species, protecting biomolecules from oxidative/carbonyl stress.
- In human cell cultures, adding L-Carnosine increases cell longevity.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745351/