L-Carnosine in the Brain: Therapeutic Perspectives

Discover the therapeutic potential of L-Carnosine in the brain. 

Abstract Summary:

  • L-Carnosine is an endogenous dipeptide found in excitable tissues like muscle and neural tissues.
  • It possesses multiple benefits, including direct and indirect antioxidant effects, anti-glycation, metal-chelating, and pH-buffering activity.
  • L-Carnosine acts as a multipotent protector against oxidative damage.
  • The role of L-Carnosine in the brain remains unclear, but it has been studied in the context of cerebral damage, such as neurodegenerative disorders and ischemic injuries.
  • The article reviews L-Carnosine's effects on both in vitro and in vivo models of cerebral damage and its physiological actions on neuronal signaling and cerebral functions.
  • In addition to its antioxidant and homeostatic properties, new potential roles of L-Carnosine in the brain are discussed.

Other Noted Benefits:

  • L-Carnosine has antioxidant, anti-glycation, and chelating properties that facilitate healthy aging.
  • It has potential therapeutic implications in neurodegenerative disorders and ischemic injuries.
  • L-Carnosine can scavenge reactive species and modulate neuronal signaling.

Source: https://pubmed.ncbi.nlm.nih.gov/30353356/

3rd Party Research

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